Antibacterial performance of chromium nanoparticles against Escherichia coli , and Pseudomonas aeruginosa

To make use of nano-sized particles for biomedical applications such nanomedicines for different diseases, it is important to study how nanoparticles behave when they interact with microorganisms. In the present study, we investigated the antibacterial performance of chromium oxide nanoparticles (Cr3O4 NPs) against two gram negative bacterial strains, Escherichia coli, and Pseudomonas aeruginosa. Chromium chloride was used as precursor to synthesize the chromium oxide nanoparticles by solution based chemical method. To study the structural analysis of prepared nanoparticles X -ray diffraction (XRD) was carried out and for magnetic behavior, Variable Sample Magnetometer (VSM) was used at room temperature. The antibacterial activity of chromium oxide nanoparticles at different concentrations was investigated against Escherichia coli (E.coli) and Pseudomonas aeruginosa (P. aeruginosa) by Kirby-Bauer disc diffusion susceptibility method. The antibacterial investigation of as prepared nanoparticle showed that chromium oxide nanoparticles (Cr3O4 NPs) can be used as antibacterial agents depending upon the concentrations used.